Objective To analyze the clinical efficacy of etofenamate gel in patients with chronic trauma of locomotion system.
Methods Randomized parallel-controlled trial was conducted. From September 2011 to March 2012, 120 patients who were diagnosed with chronic trauma of locomotion system were divided into two groups. One was etofenamate gel group (group A), and the other was diclofenac sodium cream group (group B). Treatment course was two weeks.
Results After two weeks of therapy, the effective rate of etofenamate gel was 85.0%, and of diclofenac sodium cream was 83.3%. The difference between etofenamate gel and diclofenac sodium cream had no statistical significance. Two drugs had similar efficacy in treating chronic trauma of locomotion system. Two patients in the etofenamate gel group and three in the diclofenac sodium cream group had very slight adverse reactions.
Conclusion Etofenamate gel is effective in patients with chronic trauma of locomotion system, and the efficacy is similar with diclofenac sodium cream. It is particularly suitable for patients with gastrointestinal diseases.
Citation：
TUHong-liang, TANGXu-dong. Analysis of the Clinical Efficacy of Etofenamate Gel in Patients with Chronic Trauma of Locomotion System. West China Medical Journal, 2014, 29(5): 907-909. doi: 10.7507/1002-0179.20140275
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Copyright © the editorial department of West China Medical Journal of West China Medical Publisher. All rights reserved
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- 1. 吴在德, 吴肇汉. 外科学[M]. 7版. 北京:人民卫生出版社, 2008:826.
- 2. 唐田顺, 邵成文. 中医药治疗慢性运动损伤[J]. 中医药信息, 2013, 30(3):166-167.
- 3. 邓坚真. 皮质类固醇激素局部注射副作用136例临床分析[J]. 国际医药卫生导报, 2009, 15(23):60-61.
- 4. 燕铁斌. 《中华物理医学与康复杂志》稿约[J]. 中华物理医学与康复杂志, 2005, 24(1):66-67.
- 5. 郭征, 郭霞, 邝适存, 等. 冲击波由碎石到治疗骨科疾病基础研究概述[J]. 中国矫形外科杂志, 2002, 9(7):711-713.
- 6. Ko JY, Chen HS, Chen LM. Treatment of lateral epicondylitis of the elbow with shock waves[J]. Clin Orthop Relat Res, 2001(387):60-67.
- 7. 许睿. 体外冲击波在运动系统疾病中的应用[J]. 山西师大体育学院学报, 2011, 26(2):123-125.
- 8. 朱换平, 赵兵善. 中药热敷治疗骨伤科慢性疾患的研究现状[J]. 甘肃中医学院学报, 2011, 28(5):58-61.
- 9. 李大魁. 现代临床药物学[M]. 3版. 北京化学工业出版社, 2009:248.
- 10. 冷晓梅, 曾小峰, 黄慈波, 等. 依托芬那酯凝胶治疗关节痛的多中心随机开放对照研究[J]. 中国新药杂志, 2010, 19(14):1241-1243.
- 11. 杨光复, 叶松柏. 药理学[M]. 成都:四川科学出版社, 2001:77.
- 12. 张磊. 超声波联合依托芬那酯乳膏治疗创伤性膝关节滑膜炎临床疗效观察[J]. 中国民族民间医药, 2013, 6(10):97.
- 13. 卢卫忠, 胡志芬, 周杰. 盐酸氨基葡萄糖和依托芬那酯凝胶治疗膝骨关节炎的临床研究[J]. 华西医学, 2012, 27(12):1800-1804.
- 14. 杨扬. 阳性激发点推拿联合依托芬那酯凝胶治疗颈肩背肌筋膜炎的临床观察[J]. 华西医学, 2012, 27(12):1822-1824.
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