Objective To assess the value of simplified clinical pulmonary infection score (sCPIS) in predicting prognosis of patients with ventilator-associated pneumonia (VAP).
Methods The clinical data of 52 patients with VAP,admitted in ICU between January 2011 and December 2012,were retrospectively analyzed. The sCPIS was calculated at the onset,and on 3rd,5th and 7th day after onset of VAP.
Results 24 cases survived and 28 cases died in 28-day's hospitalization. 28-day mortality was 53.8%. A significant decrease in sCPIS scores was found on 3rd,5th and 7th day after onset compared with at the onset of VAP in the survivors(4.8±1.2,4.0±1.1,3.3±1.6 vs. 5.5±1.4,P<0.05). An increase in sCPIS scores was found on 3rd,5th and 7th days after onset compared with at the onset of VAP in the non-survivors (6.8±1.3,7.5±1.4,7.8±1.2 vs. 5.8±1.5,P<0.05). The sCPIS determined at the time of VAP diagnosis and on 3rd,5th and 7th day after onset was significantly higher in the non-survivors than that in the survivors respectively (P<0.05). The duration of mechanical ventilation and the length of ICU stay were longer in the non-survivors than those in the survivors[(18.4±5.2) d vs. (12.0±4.1) d,(22.5±8.5) d vs. (16±6.3) d,P<0.05].
Conclusion Serial measurement of sCPIS is valuable in evaluating the severity of illness and predicting the prognosis.
Citation:
ZhangMin, YeXiaoling, JinJinlan, ZhangRui, ChaoShuren. Prognostic Value of Simplified Clinical Pulmonary Infection Score in Patients with Ventilator-associated Pneumonia. Chinese Journal of Respiratory and Critical Care Medicine, 2014, 13(4): 378-380. doi: 10.7507/1671-6205.2014092
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Pugin J,Auckenthaler R,Mili N,et al.Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and non bronchoscopic "blind" bronchoalveolar lavage fluid.Am Rev Respir Dis,1991,143:1121-1129.
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Luna CM,Blanzaco D,Niederman MS,et al.Resolution of ventilator-associated pneumonia:prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome.Crit Care Med,2003,31:676-682.
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