Interleukin-1 (IL-1), interleukin-2(IL-2) and interleukin-6(IL-6) activities and tumor necrosis factor (TNF) contents in plasma from patients with different sites of cancers as well as controls using bioassay technique were studied. The results showed that the levels of IL-1,IL-2,IL-6 s from patients with different sites of cancer were decreased remarkably in comparision with controls and the contents of TNF from patients with different sites of cancers increased significantly. But the difference between different sites of cancer was not statistically significant. The data suggest that the variations in the contents of TNF and the levels of interleukins may be related to the development of these caner patients.
Citation：
Meng Qingrun,Zhang Jun,Jin Hu,et al.. STUDY ON THE LEVELS OF INTERLEUKIN-1、2、6 AND THE CONTENTS OF TUMOR NECROSIS FACTOR IN THE PATIENTS WITH CANCER. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1998, 5(3): 146-147. doi:
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- 2. 张东吉. IL2的诱生与检测.见：杨贵贞，主编.免疫生物工程纲要与技术. 第1版.长春：吉林科学技术出版社， 1991∶28～51.
- 3. 吴勇. IL6的诱生与检测.见：杨贵贞，主编.免疫生物工程纲要与技术. 第1版.长春：吉林科学技术出版社， 1991∶129～142.
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- 5. Rey A, Klein B, Zagury D, et al. Diminished interleukin2 activity production in cancer patients bearing solid tumors and its relationship withnatural killer cells. Immunol Lett, 1983; 6(3)∶175.
- 6. 王江滨，谭岩，叶维法.肝癌患者外周血LAK细胞活性测定及其影响因素的研究.临床肝胆病杂志，1990； 6(4)∶183.
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