Objective To discuss the clinicopathologic risk factors related to local recurrence of rectal cancer after radical surgery.
Methods The complete clinicopathologic data of 368 patients with rectal cancer from January 2004 to April 2011 in this hospital were retrospectively analyzed by univariate and multivariate analysis methods.
Results There were 73 cases suffered from local recurrence and accounted for 19.84% (73/368) of rectal cancer during the same period. Univariate analysis results showed that gender, tumor from anal margin, tumor circumference, TNM staging, histology type, vessel infiltration, tumor perforation, stomal leak, and chemoradiotherapy were associated with postoperative recurrence (P<0.05). Multivariate analysis results showed that tumor from anal margin, tumor circumference, TNM staging, histology type, vessel infiltration, tumor perforation, and chemoradiotherapy were prognostic factor for local recurrence of rectal cancer (P<0.05).
Conclusions There are many factors related to postoperative local recurrence, but the most dangerous factor is vessel infiltration.
Citation:
YANG Jianguang,LI Zhen,LI Xiaoxia,DAI Dongqiu,.. Clinical and Pathologic Factors Analysis of Postoperative Local Recurrence of Rectal Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(11): 1200-1203. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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李小宝, 高峰, 刘勇峰, 等. 直肠癌术后局部复发原因及再手术体会[J]. 中国现代普通外科进展, 2011, 14(8):660-661.
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, 7(3):162-169.
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- 1. 薛玉龙, 刘建洛. 根治性直肠癌术后局部复发的预后分析[J]. 当代医学, 2012, 18(9):68-69.
- 2. Saito N, Koda K, Takiguchi N, et al. Curative surgery for local pelvic recurrence of rectal cancer[J]. Dig Surg, 2003, 20(3):192-199.
- 3. McCourt M, Armitage J, Monson JR. Rectal cancer[J]. Surgeon,.
- 4. Pacelli F, Tortorelli AP, Rosa F, et al. Locally recurrent rectal cancer:prognostic factors and long-term outcomes of multimodal therapy[J]. Ann Surg Oncol, 2010, 17(1):152-162.
- 5. 翁文余, 刘金龙, 周小娜. 直肠癌根治术后肿瘤复发的影响因素[J]. 实用癌症杂志, 2005, 20(3):335-336.
- 6. 丛竹军, 黄桂林, 李志刚, 等. 直肠癌术后局部复发的相关因素分析[J]. 现代肿瘤医学, 2011, 19(5):970-971.
- 7. 李世拥, 白雪. 直肠癌根治术后局部复发的因素和预防要点[J]. 中国实用外科杂志, 2011, 31(4):281-284.
- 8. Jörgren F, Johansson R, Damber L, et al. Risk factors of rectal cancer local recurrence:population-based survey and validation of the Swedish rectal cancer registry[J]. Colorectal Dis, 2010, 12(10):977-986.
- 9. Schenk JM, Kristal AR, Neuhouser ML, et al. Biomarkers of systemic inflammation and risk of incident, symptomatic benign prostatic hyperplasia:results from the prostate cancer prevention trial[J]. Am J Epidemiol, 2010, 171(5):571-582.
- 10. 刘超, 黄源. 炎症促发肿瘤转移的研究进展[J]. 国际肿瘤学杂志, 2010, 37(6):422-425.
- 11. 汪建平. 中低位直肠癌侧方淋巴结清扫的争议[J]. 外科理论与实践, 2010, 15(2):108-110.
- 12. Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-κBas the matchmaker[J]. Nat Immunol, 2011, 12(8):715-723.
- 13. 李小宝, 高峰, 刘勇峰, 等. 直肠癌术后局部复发原因及再手术体会[J]. 中国现代普通外科进展, 2011, 14(8):660-661.
- 14. 高春芳, 盛新华, 王秀丽, 等. 结直肠癌根治术后复发转移患者的预后因素分析[J]. 解放军医学杂志, 2010, 35(2):144-146, 150.
- 15. , 7(3):162-169.