Objective To approach the questions of donation after cardiac death （DCD） and transplantation through analyzing the DCD cases in this hospital.
Methods The organs were obtained from 4 DCD from 2010 to 2011 in this hospital， the clinical data of DCD were analyzed retrospectively.
Results Seven renal transplantations and 3 liver transplantations were performed. Donor warm ischemic time was 10-40 min. The liver and left kidney of the first DCD donator （Maastricht categoryⅣ） were eliminated through biopsy. One patient exhibited delayed graft function of kidney from the first DCD，the nephrectomy had to be done on day 7 after operation due to renal allograft rupture. Nine patients received 3 livers and 6 kidneys from the other 3 DCD donators （Maastricht categoryⅢ），whose patients were alive with excellent graft function.
Conclusions The use of controlled DCD （Maastricht categoryⅢ） might be an effective way to increase the number of organs available for transplantation because that it might obtain satisfactory transplant outcomes and acceptable postoperative complications. The widespread implementation of controlled DCD in China should be encouraged.
Citation：
WEI Lai,CHEN Zhishui,GUO Hui,MING Changsheng,ZENG Fanjun,ZHANG Weijie,GONG Nianqiao,LIU Bin,DU Dunfeng,CHANG Sheng,.. Ten Cases of Transplants Using Organ Donation after Cardiac Death：Experience of One Single Center. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(5): 473-477. doi:
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- 1. Bellingham JM， Santhanakrishnan C， Neidlinger N， et al. Donation after cardiac death：a 29-year experience [J]. Surgery，2011， 150(4)：692-702.
- 2. Billault C， Godfroy F， Thibaut F， et al. Organ procurement from donors deceased from cardiac death：a single-center efficiency assessment [J]. Transplant Proc， 2011， 43(9)：3396-3397.
- 3. Kim JM， Kim SJ， Joh JW， et al. Kidney donation after cardiac death in Korea [J]. Transplant Proc， 2011， 43(5)：1434-1437.
- 4. 卫生部脑死亡判定标准起草小组. 脑死亡判定标准( 成人)( 修订稿) [J]. 中国脑血管病杂志， 2009， 6(4)：220-224.
- 5. Sladen RN， Shonkwiler RJ. Donation after cardiocirculatory death：back to the future? [J]. Can J Anaesth， 2011， 58(7)：591-594.
- 6. Gok MA， Asher JF， Shenton BK， et al. Graft function after kidney transplantation from non-heartbeating donors according to Maastricht category [J]. J Urol， 2004， 172(6 Pt 1)：2331-2334.
- 7. 中华人民共和国卫生部医疗服务监管司. 卫生部办公厅关于启动心脏死亡捐献器官移植试点工作的通知( 附件1 －中国心脏死亡器官捐献分类标准. doc)[EB/OL]. http://www.moh.gov.cn/publicfiles/business/htmlfiles/zwgkzt/s9968/201104/51516.htm.
- 8. Magliocca JF， Magee JC， Rowe SA， et al. Extracorporeal support for organ donation after cardiac death effectively expands the donor pool [J]. J Trauma， 2005， 58(6)：1095-1101.
- 9. Lee JH， Hong SY， Oh CK， et al. Kidney transplantation from a donor following cardiac death supported with extracorporeal membrane oxygenation [J]. J Korean Med Sci， 2012， 27(2)：115-119.
- 10. Snoeijs MG， Boonstra LA， Buurman WA， et al. Histological assessment of pre-transplant kidney biopsies is reproducible and representative [J]. Histopathology， 2010， 56(2)：198-202.
- 11. Lo IJ， Lefkowitch JH， Feirt N， et al. Utility of liver allograft biopsy obtained at procurement [J]. Liver Transpl， 2008， 14(5)：639-646.
- 12. Ausania F， White SA， Pocock P， et al. Kidney damage during organ recovery in donation after circulatory death donors：Data from UK National Transplant Database [J]. Am J Transplant，2012 Jan 6. doi：10. 1111/j. 1600-6143. 2011. 03882. x.
- 13. Farney AC， Hines MH， al-Geizawi S， et al. Lessons learned from a single center’s experience with 134 donation after cardiac death donor kidney transplants [J]. J Am Coll Surg， 2011，212(4)：440-451.
- 14. DeOliveira ML， Jassem W， Valente R， et al. Biliary complications after liver transplantation using grafts from donors after cardiac death：results from a matched control study in a single large volume center [J]. Ann Surg， 2011， 254(5)：716-722.
- 15. Ledinh H， Weekers L， Bonvoisin C， et al. Results of kidney transplantation from controlled donors after cardio-circulatory death：a single center experience [J]. Transpl Int， 2012， 25(2)：201-209.
- 16. Bernat JL， D’alessandro AM， Port FK， et al. Report of a National conference on donation after cardiac death [J]. Am J Transplant， 2006， 6(2)：281-291.
