【Abstract】ObjectiveTo summarize the experience in diagnosis and treatment for chronic lymphocytic thyroiditis or complicated with other thyroid diseases．
MethodsSeventyseven patients were diagnosed as chronic lymphocytic thyroiditis or complicated with other thyroid diseases by operation and histological examination at this department from November 2002 to March 2005. All their clinical records including general information, the results of careful physical examination， thyroid correlated hormone tests， color Doppler, fine needle aspiration cytological examination and some intraoperative examinations have been retrospectively analyzed in this report.
ResultsThere were 53 cases of simple chronic lymphocytic thyroiditis, 10 cases complicated by papillary carcinoma， 1 case complicated by follicular carcinoma， 2 cases complicated by nonHodgkin’s lymphoma, 6 cases complicated by nodular goiter, 4 cases complicated by follicular adenoma, and 1 complicated by parathyroid adenoma. Almost all the operations were successfull and the symptoms of the diseases were alleviated. Seventytwo patients had been followed up ranging from two months to two years differently and none of them relapsed. Sixtythree of these patients have received thyrine inhibition and vicariousness treatment, 2 patients who complicated by nonHodgkin’s lymphoma had been hospitalized and 7 patients complicated by carcinoma were treated with iodine131.
ConclusionThe clinical manifestations of chronic lymphocytic thyroiditis are complex, and it often complicated with other thyroid disease, which make it difficult to diagnose the diseases before operation. However, some ancillary methods such as careful physical examination， thyroid correlated hormone tests， color Doppler and fine needle aspiration cytological examination may improve the accuracy of preoperative diagnosis. Intraoperative thyroid lamellar section and frozen histological examination are also very important for intraoperative diagnosis and operative modality selection．
Citation：
DENG Xiaofan,LI Bo,CHEN Peng.. Experience in Diagnosis and Treatment for Chronic Lymphocytic Thyroiditis (Report of 77 Cases). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2006, 13(3): 260-262下转264. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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- 4. [Ｊ]. World J Surg, 2000; 24(11)∶1290.
- 5. [Ｊ]. Head Neck Surg, 1988; 10(4)∶235.
- 6. 张波. 慢性淋巴细胞性甲状腺炎的研究进展 [Ｊ]. 国外医学·外科学分册， 1996； 23（6)∶ 331.
- 7. Mcleod MK, East ME, Burney RE, et al. Hashimoto’s thyroiditis revisited: the association with thyroid cancer remains obscure.
- 8. 夏建国, 杨尹默, 黄莚庭． 桥本病64例临床分析 [Ｊ]. 中国实用外科杂志， 1995； 15(10)∶605.
- 9. 王深明， 陈国锐. 慢性淋巴细胞性甲状腺炎合并甲亢 [Ｊ]. 广东医学， 1993； 14(1)∶6.
- 10. Ott RA, McCall AR, McHenry C, et al. The incidence of thyroid carcinoma in Hashimoto’s thyroiditis.
- 11. 杜宝昌. 桥本氏病合并甲状腺癌 [Ｊ].国外医学·外科学分册， 1994； 2l（7）∶275.
- 12. 王家耀， 廖松林， 程秀英， 等. 乔本甲状腺炎合并甲状腺乳头状癌 [Ｊ]. 中华病理杂志, 1997； 26（3）∶171.
- 13. 李树玲， 刘经祖， 李树良， 等. 甲状腺乳头状腺癌551例外科治疗远期疗效观察 [Ｊ]. 中国肿瘤临床, 1992； 19(1)∶5.
- 14. Duren M, Yavuz N, Bukey Y, et al. Impact of initial surgical treatment on survival of patients with differentiated thyroid cancer: experience of an endocrine surgery center in an iodinedeficient region.
- 15. Calabro S, Auguste LJ, Attie JN. Morbidity of completion thyroidectomy for initially misdiagnosed thyroid carcinoma.
- 16. 蔡伟耀. 分化型甲状腺癌甲状腺切除范围的争论 [Ｊ]. 外科理论与实践, 2003; 8(4)∶290.
- 17. Thompson NW, Harness JK. Complications of total thyroidectomy for carcinoma [Ｊ]. Surg Gynecol Obstet,1970； 131(5)∶861.
